epi’s Post

Hello patent people. If you are interested in claiming microbes, take a look at our article about depositing them first!

The complexity of biological systems makes developing any new drug challenging. To streamline the collaboration between biologists and chemists, we've developed a more integrated approach: our BioELN solution. Learn more: http://ms.spr.ly/6042gNfc2 #DrugDiscovery #DrugDevelopment

A potentially interesting set for anybody building focused phenotypic libraries or in need of chemical probes for target discovery/validation. Using EMBLs ChEMBL dataset we identified 10 000+ stock compounds directly available from commercial sources. Tag someone who could benefit from this valuable resource or share to spread the word! 🤝 #DrugDiscovery #ChemicalProbes #Innovation #EMBL #ChEMBL #PhenotypicLibraries #PDD

European ban on patents for New Genomic Techniques (NGT) plants? The European Parliament has voted to adopt a proposal that would limit the possibility of protecting NGT (genetically amended) plants via patents. The ban is part of a greater European plan to allow certain NGT plants on the European market, a debate that has long been a divisive issue in Europe. While a solution for commercializing NGT plants in Europe was much needed and long overdue, it is unclear how a possible ban on plant patents fits into this debate, let alone should be practically implemented. For instance, it would require a change in the European Patent Convention, which is not straightforward. Hence, companies in the agro sector continue to be faced with uncertainties on how their innovations can be protected. It seems that by trying to solve one crucial problem for the sector, the EU simply introduced another...

Meridian’s Low DNA Taq HS is a highly purified, chemically modified hot start Taq that is ideal for workflows requiring room-temperature reaction setup. In high throughput settings where large-volume sample preparation may take an extended period of time, hot-start polymerases are essential to prevent nonspecific amplification and the formation of primer dimers. Free from animal-derived compounds, Low DNA Taq HS minimizes the potential for background contamination or DNA contamination, which is especially important for the detection of bacterial targets such as E. coli. The enzyme is completely inactive at room temperature and requires a 10-minute incubation at 95°C to release its functional activity. Contact us to learn more or request a sample! #moleculardiagnostics #pcr

UPDATED POSTER: Phytocannabinoid Guide: Biosynthesis, Naming, & Numbering: Download PDF or request a physical copy ► https://loom.ly/5imMME0 This lab wall poster presents the biosynthesis and degradation pathways of phytocannabinoids derived from the olivetol, varinol, and orcinol series and explains the conventions that have been adopted for nomenclature and structure numbering systems.

Le et al. demonstrate formation of AAV-like particles in E. coli. Although these particles consist of VP3-only empty capsids, the authors showed that they could be taken up into cells. Further work in this field may build upon these results and aid development of approaches for AAV manufacturing. It should be noted that producing clinically useful AAVs in bacteria is a fair ways off, but this study provides some useful insights that may inform future manufacturing efforts. #biotech #genetherapy #syntheticbiology https://lnkd.in/ge2BgdUQ

Meridian’s Low DNA Taq HS is a highly purified, chemically modified hot start Taq that is ideal for workflows requiring room-temperature reaction setup. In high throughput settings where large-volume sample preparation may take an extended period of time, hot-start polymerases are essential to prevent nonspecific amplification and the formation of primer dimers. Free from animal-derived compounds, Low DNA Taq HS minimizes the potential for background contamination or DNA contamination, which is especially important for the detection of bacterial targets such as E. coli. The enzyme is completely inactive at room temperature and requires a 10-minute incubation at 95°C to release its functional activity. Contact us to try a sample: https://lnkd.in/g3yrGCsv #moleculardiagnostics